Amanda is a divorced woman who makes a living as a photographer. During the Fall of the year Amanda begins to see the world in new and different ways when she begins to question her role in life, her relationships with her career and men and what it all means. As the layers to her everyday experiences fall away insertions in the story with scientists, and philosophers and religious leaders impart information directly to an off-screen interviewer about academic issues, and Amanda begins to understand the basis to the quantum world beneath. During her epiphany as she considers the Great Questions raised by the host of inserted thinkers, she slowly comprehends the various inspirations and begins to see the world in a new way.
Unfortunately the movie What the #$*! Do We (K)now!? is not yet available on Disney Plus.
| Directing | William Arntz | Director |
| Directing | Betsy Chasse | Director |
| Sound | Christopher Franke | Original Music Composer |
| Camera | David Bridges | Director of Photography |
| Camera | Mark Vicente | Director of Photography |
| Directing | Mark Vicente | Director |
| Writing | William Arntz | Writer |
| Writing | Betsy Chasse | Writer |
| Writing | Mark Vicente | Writer |
| Production | William Arntz | Producer |
| Production | Betsy Chasse | Producer |
| Production | Todd C. Guzze | Producer |
| Production | Mark Vicente | Producer |
| Editing | Jonathan P. Shaw | Editor |
| Art | Nava | Production Design |
| Costume & Make-Up | Ronald Leamon | Costume Design |
| Costume & Make-Up | E. Larry Day | Makeup Department Head |
| Costume & Make-Up | E. Larry Day | Hair Department Head |
| Directing | Eugene Mazzola | Assistant Director |
