A beautiful school is about to reopen after many years and Luì and Sofì (Me against You) are the special guests of the inauguration party, their friend Pongo awaits them there. The school, however, could hide a mystery and, once again, the Me against You will have to face the evil Mr. S with courage and try to sabotage his evil plans in the name of friendship. In the school, for the first time, Luì and Sofì could learn an important secret about their past. A new “magical” adventure in the cinema for Luì and Sofì, in a world of magic, with lots of surprises and fun for their little fans and all families.
Unfortunately the movie It's me against you - The mystery of the spellbound school is not yet available on Disney Plus.
| Costume & Make-Up | Tecla Turiaco | Costume Design |
| Sound | Fabio Felici | Sound |
| Production | Giusy Marrone | Casting |
| Writing | Emanuela Canonico | Screenplay |
| Writing | Andrea Boin | Screenplay |
| Writing | Luigi Calagna | Screenplay |
| Writing | Sofia Scalia | Screenplay |
| Production | Gaia Antifora | Executive Producer |
| Production | Simone Tacchia | Line Producer |
| Art | Francesco Scandale | Art Direction |
| Art | Melissa Fasolino | Set Decoration |
| Production | Antonio Tacchia | Production Manager |
| Production | Flavia Scardini | Production Manager |
| Crew | Alessandro Baragli | Post Production Supervisor |
| Production | Elisabetta Ariemma | Production Assistant |
| Directing | Laura Orrù | Continuity |
| Directing | Laura Orrù | Script Supervisor |
| Visual Effects | Nuccio Canino | Visual Effects Supervisor |
| Production | Maurizio Totti | Producer |
| Directing | Gianluca Leuzzi | Director |
| Production | Luigi Calagna | Producer |
| Production | Sofia Scalia | Producer |
| Writing | Luigi Calagna | Story |
| Writing | Sofia Scalia | Story |
| Camera | Davide Crippa | Director of Photography |
| Editing | Davide Cerfeda | Editor |
| Art | Mario Torre | Production Design |
| Sound | Stefano Della Casa | Original Music Composer |
