Dr. Frankenstein and her assistant, Dr. Yanco, are going to bring one of their experiments to life in Santo Vs. Frankenstein's Daughter. She intends to use a monster named Ursus to do her evil bidding. Using a youth serum to retain their vitality, the doctors set their sights upon none other than El Santo. They need his super human blood to regenerate a stronger youth serum. They kidnap Santo's goddaughter, Norma and lure him into Dr. Frankenstein's lab where he is captured and enslaved. Will Santo make it out alive?
Unfortunately the movie Santo vs. Frankenstein's Daughter is not yet available on Disney Plus.
| Editing | Jorge Busto | Editor |
| Camera | Raúl Martínez Solares | Director of Photography |
| Production | Guillermo Calderón | Producer |
| Directing | Miguel M. Delgado | Director |
| Production | El Santo | Producer |
| Writing | Fernando Osés | Story |
| Sound | Gustavo César Carrión | Music Director |
| Costume & Make-Up | Román Juárez | Makeup Artist |
| Editing | Joaquín Ceballos | Assistant Editor |
| Art | José Rodríguez Granada | Production Design |
| Art | Adalberto López | Set Decoration |
| Writing | Fernando Osés | Adaptation |
