After old Trowbridge is mysteriously murdered, his nephew, Kane Langdon, is accused of the crime. Trowbridge's adopted daughter Alice makes every effort to prove Kane's innocence, but to no avail. When Kane escapes from the clutches of the law, Alice works with him to investigate the crime. They soon discover that Judge Hoyt, a great friend of Trowbridge and an ardent admirer of Alice, killed Trowbridge after forging the old man's will to read that Alice would only inherit his fortune if she married the judge. The judge, confronted with the accusation, becomes so unnerved that he confesses to the crime, and all ends happily with Alice in Kane's arms.
Unfortunately the movie The Mark of Cain is not yet available on Disney Plus.
| Directing | George Fitzmaurice | Director |
| Writing | Philip Bartholomae | Scenario Writer |
| Writing | Carolyn Wells | Story |
| Camera | Arthur C. Miller | Director of Photography |
| Art | William Cameron Menzies | Art Direction |
